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New drug combo tested for tough bile duct cancers

NCT ID NCT05712356

First seen May 26, 2026 · Last updated Jun 17, 2026 · Updated 6 times

Summary

This study tested a new drug called LSTA1 added to standard treatment for people with advanced bile duct or gallbladder cancer. The goal was to see if the combination is safe and works better than standard treatment alone. The trial was stopped early, and results are not yet available.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Alliance for Multispecialty Research

    Merriam, Kansas, 66204, United States

  • Banner MD Anderson Cancer Center

    Gilbert, Arizona, 85234, United States

  • Carl & Edyth Lindner Center for Research & Education at The Christ Hospital and The Christ Hospital Cancer Center

    Cincinnati, Ohio, 45219, United States

  • FirstHealth of the Carolinas, Inc.

    Pinehurst, North Carolina, 28374, United States

  • Inova Schar Cancer Institute

    Fairfax, Virginia, 22031, United States

  • Mayo Clinic Arizona

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55905, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Northwell Health - Zuckerberg Cancer Center

    Lake Success, New York, 11042, United States

  • Norton Cancer Institute, Audubon

    Louisville, Kentucky, 40217, United States

  • Norton Cancer Institute, Downtown

    Louisville, Kentucky, 40202, United States

  • Spartanburg Medical Center

    Spartanburg, South Carolina, 29303, United States

  • Stony Brook Cancer Center

    Stony Brook, New York, 11794, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • University of Arizona Cancer Center

    Tucson, Arizona, 85719, United States

  • University of Kansas Cancer Center

    Westwood, Kansas, 66205, United States

  • University of Kentucky Medical Center

    Lexington, Kentucky, 40536, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

Conditions

The condition(s) this trial relates to.

bile duct cancer bile duct neoplasm cholangiocarcinoma Disease Progression extrahepatic bile duct carcinoma gallbladder cancer gallbladder carcinoma gallbladder neoplasm intrahepatic cholangiocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.