New injection could ease jaw pain better than standard treatment
NCT ID NCT07075276
First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 31 times
Summary
This study compares a new injection of liquid phase concentrated growth factor (LPCGF) to standard arthrocentesis (joint washing) for people with painful jaw clicking and limited mouth opening due to a displaced disc. Thirty-two adults aged 18-45 with unilateral disc displacement will be randomly assigned to one of the two procedures. The goal is to see if LPCGF reduces pain and improves mouth opening more than the conventional treatment.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Faculty of Dentistry- Horus University in Egypt
RECRUITINGDamietta, New Damietta, 34518, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Liquid Phase Concentrated Growth Factor (LPCGF)
What this could lead to
If it works, this could offer a more effective, less invasive option for treating painful jaw clicking and limited mouth opening.
What could go wrong
This is a small, early-stage trial with only 32 participants, so results may not apply to everyone. The treatment is compared to a standard procedure, and benefits may be modest.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.