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Can a lozenge fight gum disease? tiny study says maybe

NCT ID NCT06819761

Knowledge-focused Sponsor: Ostia Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tested whether a lozenge could deliver helpful bacteria (SALI-10 probiotics) to the mouth. Eight healthy adults took the lozenge, and researchers measured changes in oral bacteria and inflammation after one week. The goal was to see if the lozenge is a practical way to improve gum health.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

8 people

The number who actually took part.

Started

Mar 2025

Finished

Jun 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Male or female volunteers aged 18-70 years 2. In good general health, ASA I 3. Non-smokers 4. Fluent in English Exclusion Criteria: 1. Presence of orthodontic bands. 2. Presence of partial removal dentures. 3. Dental pain at time of screening. 4. History of allergy to a consumer or personal care products or dentifrice ingredients as determined by the dental profession monitoring the study. 5. Participation in any other clinical study or test panel within one month before entering the study. 6. Current use of anti-inflammatory, antibiotics, or antimicrobial drugs or within the last 30 days of enrolment. 7. History of periodontal disease. 8. History of systemic inflammatory or immune conditions 9. Pregnant or nursing women. 10. Use of tobacco products. 11. Long-term antibiotic or anti-inflammatory therapy. 12. Medical condition or any current usage of medication that the investigator considers may compromise the subject's safety as well as the quality of the study results; 13. Use of any concomitant medication.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Delivery systems Oral health

Contacts and locations

Locations

  • Ostia Sciences Inc

    Toronto, Ontario, M5G 1G6, Canada

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