New pill shows promise for Hard-to-Treat blood cancers
NCT ID NCT05024045
First seen Mar 04, 2026 · Last updated Apr 29, 2026 · Updated 7 times
Summary
This early-stage study tests an experimental pill called LOXO-338 in people with advanced blood cancers (like leukemia, lymphoma, or multiple myeloma) who have already tried standard treatments. The main goals are to find a safe dose and see if the drug can shrink tumors or improve blood counts. About 316 participants will take the drug for up to 3 years, and some may also receive a second drug called pirtobrutinib.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHRU de Montpellier-Hopital St Eloi
Montpellier, 34295, France
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Centre Hospitalier Lyon Sud
Pierre-Bénite, Cedex, 69495, France
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Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu
Nantes, 44093, France
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Centre hospitalier universitaire de Haut Leveque
Pessac, 33604, France
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Centrum Medyczne Pratia Poznan
Skorzewo, Poznan, 60 185, Poland
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City of Hope National Medical Center
Duarte, California, 91010-0269, United States
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Emory University
Atlanta, Georgia, 30322, United States
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IRCCS - AOU di Bologna
Bologna, 40138, Italy
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Indiana Blood & Marrow Transplantation (IBMT)
Indianapolis, Indiana, 46237, United States
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Institut Curie
Paris, 75248, France
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L'Institut Universitaire du Cancer de Toulouse Oncopole
Toulouse, Cedex 9, 31100, France
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Mayo Clinic
Rochester, Minnesota, 55905-0002, United States
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Mayo Clinic in Florida
Jacksonville, Florida, 32224, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie Panstwowy Instytut Badawczy
Warsaw, 02-781, Poland
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Pratia MCM Krakow
Krakow, 30-510, Poland
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Swedish Medical Center
Seattle, Washington, 98104, United States
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Sylvester Comprehensive Cancer Center
Miami, Florida, 33136, United States
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The University of Arizona Cancer Center
Tucson, Arizona, 85724, United States
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Tufts Medical Center
Boston, Massachusetts, 02111, United States
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University of California San Francisco, Medical Center at Paranassus
San Francisco, California, 94117, United States
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University of Kansas Medical Center
Westwood, Kansas, 66205, United States
Conditions
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