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Could new CT scans use less radiation without losing clarity?

NCT ID NCT02417714

Knowledge-focused Sponsor: National Heart, Lung, and Blood Institute (NHLBI) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 15, 2026 · Updated 14 times

Summary

This study tests whether new CT imaging methods that use less radiation can produce pictures as clear as standard CT scans. About 215 healthy adults scheduled for a chest, abdomen, and pelvis CT will get one extra low-radiation scan. Researchers will compare image quality between the two methods.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to safer CT scans with lower radiation exposure for patients.
What could go wrong
This is an early-stage imaging study, not a treatment trial. The new methods may not match standard image quality in all cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 215 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2014

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

A government research agency

The lead sponsor is the US National Institutes of Health.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants will be enrolled at the NIH Clinical Center. A total of 215 subjects will be enrolled. Subjects will be recruited from the NIH Clinical Center radiology department from subjects scheduled to have a CT scan of the chest, abdomen and pelvis with contrast.

Ages

18 to 99 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

* INCLUSION CRITERIA: Inclusion Criteria for Body CT: 1. Clinical indication for a chest, abdomen and pelvis CT with contrast 2. Age equal to or greater than 18 years 3. Able to understand and willing to sign the Informed Consent Form Inclusion Criteria for Chest CT: 1. Clinical indication for a CT with or without contrast that includes the chest 2. Age equal to or greater than 18 years 3. Able to understand and willing to sign the Informed Consent Form EXCLUSION CRITERIA: Exclusion Criteria for Body CT: 1. Pregnancy 2. Serum Cr \> 1.5 mg/dL 3. Clinical CT scan with more than one contrast imaging phase (for example three phase liver) Exclusion Criteria for Chest CT 1\. Pregnancy

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy subjects

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

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