Muscle mass may predict COPD prognosis, study finds
NCT ID NCT07541053
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study from Mansoura University looked at how low fat-free mass (muscle) affects the outlook for people with COPD. Researchers studied 90 adults aged 40 and older with confirmed COPD. They used breathing tests, a 6-minute walk test, CT scans, and the BODE index to measure health. The goal was to see if low muscle mass is linked to worse COPD outcomes.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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90 people
The number who actually took part.
- Started
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Apr 2024
- Finished
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Apr 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
* Group A: COPD patients with low FFM which is defined as fat-free mass refers primarily to muscle mass, especially while considering body composition and weight management. * Group B: COPD patients with normal FFM with matched age and sex to the patients group.
- Ages
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40 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Were adults aged ≥40 years with a clinical diagnosis of COPD confirmed by spirometry showing post-bronchodilator FEV₁/FVC \<0.70 according to GOLD 2024 criteria Exclusion Criteria: * Exacerbation within the preceding month, active pulmonary infection, physical disability precluding study measurements (e.g., musculoskeletal or neurological disorders), advanced heart failure (NYHA class III-IV), malignancy or hyperthyroidism.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mansoura Univeristy Chest Medicine
Al Mansurah, Egypt
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