Can a tiny dose of norepinephrine during surgery save lungs?
NCT ID NCT07627360
First seen Jun 08, 2026 · Last updated Jun 19, 2026 · Updated 3 times
Summary
This study tests whether giving a low, steady dose of norepinephrine during laparoscopic abdominal surgery can reduce the amount of IV fluids needed and lower the risk of lung complications afterward. It includes 130 adults at high risk for lung problems. The drug is given from the start of anesthesia until the surgery ends, and the results are compared to a placebo.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Suez Canal University Hospitals
Ismailia, Ismailia Governorate, 41522, Egypt
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
norepinephrine
What this could lead to
If it works, this could point toward a safer way to manage blood pressure during surgery, reducing fluid overload and lung complications.
What could go wrong
This is a small, early-phase trial with only 130 patients, so results may not apply to everyone. Norepinephrine can cause side effects like rapid heart rate or high blood pressure.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.