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Can less dye and less radiation still spot appendicitis?

NCT ID NCT05878665

Diagnosis Sponsor: Bohyun Kim Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 09, 2026 · Last updated Sep 10, 2026 · Updated 1 time

Summary

Researchers are testing a CT scan that uses less contrast dye and lower radiation to diagnose appendicitis in young adults. The study compares this low-dose approach against standard dosing to see if it still gives accurate results. Participants are emergency patients with suspected appendicitis who need a contrast-enhanced CT. The goal is to find out how much iodine and radiation can be safely reduced without missing the diagnosis.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
low-dose contrast media with low-radiation CT scan
What this could lead to
If it works, this approach could let doctors diagnose appendicitis with less contrast dye and lower radiation, which matters for young patients who may need repeated scans.
What could go wrong
The lower contrast dose might make images too blurry to spot appendicitis reliably, and the study is small and limited to young adults with a healthy weight, so results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

109 people

The number who actually took part.

Started

Dec 2023

Finished

Sep 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 44 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * Patients in the emergency department with suspected acute appendicitis based on clinical examination * Patients scheduled for contrast-enhanced CT of the abdomen and pelvis for diagnosis of suspected acute appendicitis. Exclusion criteria: * Patients who decline to participate * Contraindications to contrast-enhanced CT (eGFR \< 30 mL/min/173 m\^2 or pregnant) * BMI \>= 30.

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Conditions

The condition(s) this trial relates to.

Abdomen, Acute appendicitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Appendicitis acute

Contacts and locations

Locations

  • Seoul St. Mary's Hospital

    Seoul, 06591, South Korea

More trials for these conditions

Other studies related to the condition(s) this trial covers.