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Could a weaker anesthetic block keep you moving after hip surgery?

NCT ID NCT06102811

Symptom relief Sponsor: University of Toronto Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two strengths of a nerve block (fascia iliaca block) for pain after hip replacement surgery. Sixty adults received either a low or high concentration of the anesthetic ropivacaine. The goal was to see if the low dose could control pain just as well while avoiding leg muscle weakness. Researchers measured muscle strength and pain scores in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ropivacaine
What this could lead to
If it works, this could provide effective pain relief after hip replacement without causing leg weakness, helping patients recover faster.
What could go wrong
This is a small, completed study with only 60 participants. The low-dose block may not control pain as well as the standard dose, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Oct 2023

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients undergoing primary THA in the inpatient setting. * Non-pregnant patients older than 21 years of age. * Patients with American Society of Anesthesiologists (ASA) physical status I-IV. * No alcohol or drug dependency. Exclusion Criteria: * Patients undergoing outpatient THA. * Chronic opioid use of 30 mg or more of oral morphine equivalent, per day, for the last 2 consecutive weeks. * Contraindications for nerve block placement (severe anatomic abnormalities, local or systemic infection). * Contraindications for any of the standardized medications used for the study (Mepivacaine, Fentanyl, Dexamethasone, Ondansetron, Acetaminophen, Celecoxib, Hydromorphone). * Not submitted to the standardized spinal anesthesia technique. * Need to conversion to general anesthesia after the start of the surgery.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Arthroplasty, replacement, hip

Contacts and locations

Locations

  • Mount Sinai Hospital

    Toronto, Ontario, M5G 1X5, Canada

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