Hope for FSHD: experimental drug losmapimod put to the test
NCT ID NCT04264442
First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 30 times
Summary
This study tested a drug called losmapimod in 76 adults with facioscapulohumeral muscular dystrophy (FSHD), a rare disease that causes muscle weakness. The goal was to see if the drug is safe and can help control the disease. Participants received either losmapimod or a placebo for 48 weeks, and some continued in an open-label extension. The trial was terminated early, but results focus on safety and side effects.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU de NICE- CHU pasteur2
Nice, 06001, France
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Hospital UiP La Fe
Valencia, 46026, Spain
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Hospital de la Sta Creu i St Pau
Barcelona, 08041, Spain
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Kennedy Krieger Institute
Baltimore, Maryland, 21205, United States
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Montreal Neurological Institute and Hospital
Montreal, Quebec, H3A 2B4, Canada
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Ohio State University
Columbus, Ohio, 43221, United States
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Ottawa Hospital Research Institute
Ottawa, Ontario, K1Y 4E9, Canada
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University of California Irvine
Irvine, California, 92868, United States
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University of California Los Angeles (UCLA)
Los Angeles, California, 90095, United States
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University of Florida
Gainesville, Florida, 32610, United States
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University of Kansas Medical Center
Kansas City, Kansas, 66160, United States
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University of Massachusetts Memorial Medical Center
Worcester, Massachusetts, 01655, United States
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University of Rochester Medical Center
Rochester, New York, 14642, United States
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University of Utah
Salt Lake City, Utah, 84132, United States
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University of Washinton Medical Center
Seattle, Washington, 98195, United States
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Virginia Commonwealth University
Richmond, Virginia, 23298, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
Conditions
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