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New Silver-Coated plates aim to cut infection risk in broken ankles

NCT ID NCT05260463

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study tested special silver-coated metal plates used to fix broken ankle bones. The goal was to see if these plates are safe and reduce infections compared to standard uncoated plates. 203 adults with distal fibula fractures took part. The results showed the silver-coated plates were safe and had a similar infection rate to standard plates.

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Contacts and locations

Locations

  • Agaplesion Bethesda Krankenhaus Wuppertal

    Wuppertal, 42109, Germany

  • Helios Klinikum Berlin-Buch GmbH

    Berlin, 13125, Germany

  • Helios Universitätsklinikum Wuppertal

    Wuppertal, 42283, Germany

  • Städtisches Klinikum Dresden

    Dresden, 01067, Germany

  • Unfallkrankenhaus Berlin

    Berlin, 12683, Germany

  • Universitätsklinikum Carl Gustav Carus Dresden

    Dresden, 01307, Germany

  • Universitätsklinikum Freiburg

    Freiburg im Breisgau, 79106, Germany

  • Universitätsklinikum Gießen-Marburg

    Giessen, 35385, Germany

  • Universitätsklinikum Homburg-Saar

    Homburg, 66421, Germany

  • Universitätsklinikum Leipzig

    Leipzig, 04103, Germany

  • Universitätsklinikum Münster

    Münster, 48149, Germany

  • Universitätsklinikum Regensburg

    Regensburg, Bavaria, 93042, Germany

  • Universitätsklinikum Rostock

    Rostock, Germany

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

silver-coated locking plate

What this could lead to

If successful, this could provide a safer option for treating ankle fractures by reducing the chance of infection after surgery.

What could go wrong

This is a completed early-stage study, so larger trials are needed to confirm benefits. Silver allergy or device-related side effects are possible risks.

Conditions

The condition(s) this trial relates to.

bone fracture Fibula Fractures Fractures, Closed Fractures, Open Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.