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New hope for MLD: Long-Term drug safety trial completed

NCT ID NCT01887938

First seen Jan 10, 2026 · Last updated May 18, 2026 · Updated 17 times

Summary

This study looked at the long-term safety of a drug called HGT-1110 for people with metachromatic leukodystrophy (MLD), a rare and serious brain disease. It included 24 people who had already been in an earlier study of the same drug. The main goal was to track side effects and see if the body made antibodies against the drug over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHR Orleans - Hopital La Source

    Orléans, 45067, France

  • CHU de Nantes

    Nantes, 44093, France

  • Center for Pediatric Clinical Studies (CPCS)

    Tübingen, Baden-Wurttemberg, 72076, Germany

  • Detska Interni Klinika, Lf Mu A Fn Brno

    Brno, 61300, Czechia

  • Hopital Femme Mere Enfant

    Bron, 69 677, France

  • Hopital Gui de Chauliac - CHRU de Montpellier

    Montpellier, 34000, France

  • Hospital de Clinicas de Porto Alegre

    Porto Alegre, 90035-003, Brazil

  • Hôpital de Bicêtre

    Le Kremlin-Bicêtre, Île-de-France Region, 94275, France

  • Kitakyushu Municipal Yahata Hospital

    Fukuoka, 805-8534, Japan

  • Klinikum Oldenburg

    Oldenburg, 26133, Germany

  • Kurashiki Central Hospital

    Okayama Prefecture, 710-8602, Japan

  • Marien-Hospital Wesel gGmbh

    Wesel, 46483, Germany

  • Osaka University Hospital

    Osaka, 565-0871, Japan

  • Rigshospitalet

    Copenhagen, 2100, Denmark

  • The Children's Hospital at Westmead

    Westmead, 2145, Australia

Conditions

Explore the condition pages connected to this study.