COVID lung damage lingers months later, new study reveals
NCT ID NCT04422613
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 73 people who were hospitalized with severe COVID-19 pneumonia to see if their lungs still had problems 4 months later. The main focus was on how well oxygen moves from the lungs into the blood. The goal was to better understand these lasting issues so doctors can help patients recover more effectively.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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73 people
The number who actually took part.
- Started
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May 2020
- Finished
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Oct 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient with COVID-19 pneumonia * Positive PCR for COVID-19 on respiratory sample (saliva, nasopharyngeal, bronchial, tracheal aspiration or LBA) * Having required hospitalization in the pulmonology service, intensive care in pneumology or resuscitation service at the Toulouse University Hospital * Saturation \<94% in ambient air at diagnosis * Patient having a chest CT-scan proving pneumonia during his hospitalization * Patient ≥ 18 years old * Patient who has given written consent to participate in the study Exclusion Criteria: * Patient hospitalized for pneumonia not documented by a chest CT-scan * Patient with negative COVID PCR * Patient known before the episode of COVID-19 pneumonia for a respiratory or cardiac pathology which can lead in itself to an alteration of gas exchanges * Patient under curators / guardianship * Pregnant patient * Minor patient * Absence of consent for participation in the study * Medical condition that does not allow for pulmonary function test
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital of Toulouse
Toulouse, 31000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Placenta cells tested as COVID fighter – but trial stopped early
- New alert system aims to cut unnecessary antibiotics in pneumonia patients
- New drug AV-001 aims to help hospitalized pneumonia patients breathe easier
- Could a simple gas stop COVID-19 from getting worse?
- What happens to the sickest COVID patients? french ICU study aims to find out