Does an extra knee ligament procedure lead to arthritis later?
NCT ID NCT06885372
First seen May 17, 2026 · Last updated Jun 23, 2026 · Updated 7 times
Summary
This study follows 510 people who had ACL knee reconstruction surgery, with or without an extra procedure called LET, about 10 years ago. Researchers want to see if adding LET increases the chance of developing knee osteoarthritis. Participants will get X-rays and answer questions about knee pain and function. The goal is to help doctors and patients weigh long-term risks when choosing treatment.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Banff Sport Medicine Clinic
Banff, Alberta, T1L 1B3, Canada
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Fowler Kennedy Sport Medicine Clinic
London, Ontario, N6A 3K7, Canada
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Fraser Health Authority
New Westminster, British Columbia, V3L 5P5, Canada
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McMaster University
Hamilton, Ontario, L8N 3Z5, Canada
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Pan Am Clinic
Winnipeg, Manitoba, R3M 3E4, Canada
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Queens University
Kingston, Ontario, K7L 2V7, Canada
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University Hospitals Coventry and Warwickshire NHS Trust
Coventry, CV2 2DX, United Kingdom
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University of Calgary
Calgary, Alberta, T2N 1N4, Canada
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lateral Extra-Articular Tenodesis (LET) procedure
What this could lead to
If successful, this study will clarify whether adding LET to ACL reconstruction raises the risk of knee osteoarthritis, helping surgeons and patients make better-informed decisions.
What could go wrong
This is an observational follow-up, not a new treatment test. Results may show no clear link or may not apply to all patients. The study relies on imaging and patient reports, which can vary.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.