Does the EV71 vaccine last? new study checks kids years later
NCT ID NCT07630493
First seen Jun 07, 2026 · Last updated Jun 19, 2026 · Updated 2 times
Summary
This study looks at whether an inactivated enterovirus 71 (EV71) vaccine still protects children two to two-and-a-half years after the last dose. It involves 126 healthy children from Vietnam who received the vaccine in an earlier phase 3 trial. Researchers will take a blood sample to measure neutralizing antibody levels, which indicate how well the immune system remembers the virus. No new vaccine is given in this extension study.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Centers for Disease Control and Prevention, Vinh Long Province, Vietnam
Vĩnh Long, Vinh Long Province, Vietnam
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
EnVAX-A71 (inactivated enterovirus 71 vaccine with adjuvant)
What this could lead to
If successful, this could show that the EV71 vaccine provides long-lasting protection against hand, foot, and mouth disease caused by enterovirus 71.
What could go wrong
This is an extension study with no new vaccine doses given, so it only measures immune response over time. It does not test whether the vaccine still prevents infection, and the small sample size limits how much we can conclude.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.