Does the EV71 vaccine last? new study checks kids years later
NCT ID NCT07630493
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether an inactivated enterovirus 71 (EV71) vaccine still protects children two to two-and-a-half years after the last dose. It involves 126 healthy children from Vietnam who received the vaccine in an earlier phase 3 trial. Researchers will take a blood sample to measure neutralizing antibody levels, which indicate how well the immune system remembers the virus. No new vaccine is given in this extension study.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- EnVAX-A71 (inactivated enterovirus 71 vaccine with adjuvant)
- What this could lead to
- If successful, this could show that the EV71 vaccine provides long-lasting protection against hand, foot, and mouth disease caused by enterovirus 71.
- What could go wrong
- This is an extension study with no new vaccine doses given, so it only measures immune response over time. It does not test whether the vaccine still prevents infection, and the small sample size limits how much we can conclude.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centers for Disease Control and Prevention, Vinh Long Province, Vietnam
Vĩnh Long, Vinh Long Province, Vietnam
More trials for these conditions
Other studies related to the condition(s) this trial covers.