CAR t cell patients monitored for years to uncover Long-Term effects
NCT ID NCT05024175
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 45 adults who previously received CAR T cell therapy in earlier trials. Researchers will track their health for years using scans, blood tests, and physical exams to see how long the treatment's effects last and whether any late side effects appear. The goal is to better understand the long-term safety and success of CAR T cells.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- CAR T cells
- What this could lead to
- If successful, this study will provide crucial data on the long-term safety and effectiveness of CAR T cell therapy, helping to improve future treatments.
- What could go wrong
- This is an observational follow-up study, not a new treatment trial. It cannot prove that CAR T cells work long-term, and results may be limited by the small number of participants.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 45 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Aug 2023
- Expected to finish
-
Aug 2039
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Subjects will be asked to participate leading up to the last DF/HCC corresponding main study visit
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Subjects will be asked to participate leading up to the last DF/HCC corresponding main study visit. Subjects meeting the following criteria are eligible for study participation: * Provision of voluntary written informed consent by subject * CAR T cells were administered in DF/HCC IRB corresponding main study Exclusion Criteria: Subjects meeting the following criterion are to be excluded from study participation: \- Subject unable to comply with study requirements
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Adult are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Pfizer tests RSV vaccine aimed at older adults
- Dye-Guided surgery may spare healthy lymph nodes in esophageal cancer
- What does a healthy mouth mean for people with disabilities?
- Hidden toll of routine ICU procedure revealed: suctioning may spike pain and stress
- New drug duo takes on recurrent brain cancer
- Spinach showdown: does how It's grown affect your blood pressure?