Spinach showdown: does how It's grown affect your blood pressure?
NCT ID NCT07665944
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether smoothies made from hydroponically grown spinach affect nitrate levels in saliva and blood pressure differently than those made from conventionally grown spinach. Twelve healthy adults will drink both types of smoothies on separate days, with measurements taken before and after. The goal is to see if the growing method changes the health benefits.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Spinach smoothie (hydroponically or conventionally grown)
- What this could lead to
- If it works, this could show that hydroponic spinach provides similar or better nitrate benefits than conventional spinach, potentially guiding healthier food choices.
- What could go wrong
- This is a very small (12 participants), early-stage trial measuring short-term effects only. Results may not apply to the general population or long-term health.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 12 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18-60 years * Generally healthy individuals (no diagnosed chronic disease) * Non-smokers and non-vapers * Not currently taking medications known to affect cardiovascular function or nitrate metabolism * Able and willing to provide informed consent * Willing to comply with study procedures and attend both study visits Exclusion Criteria: * Presence of chronic disease (e.g., cardiovascular, metabolic, renal, or respiratory conditions) * Use of pacemakers or implanted medical devices * Pregnant or lactating individuals * Known allergy or intolerance to spinach * History of gastrointestinal disorders or pathology affecting digestion or absorption * Use of nitrate or nitrite supplements * Use of antibiotics within the past 3 weeks * Use of antibacterial mouthwash or oral products within the past 2 weeks * Current participation in another clinical trial or recent participation that may interfere with outcomes
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Plymouth
RECRUITINGPlymouth, Devon, PL4 6AB, United Kingdom
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