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Childhood radiation for benign tumors may affect adult brain function

NCT ID NCT01960751

Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at adults who received low-dose radiation to the brain as children for a non-cancerous skin growth. Researchers want to see if this radiation caused any long-term thinking or memory problems. About 150 participants will take memory and thinking tests to compare those who got higher versus lower doses.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help identify risk factors and brain structures affected by low-dose radiation, potentially guiding future monitoring or treatments.
What could go wrong
This is an observational study with no new treatment being tested. Results may not apply to other conditions or radiation doses.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

119 people

The number who actually took part.

Started

Apr 2014

Finished

Feb 2015

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subject treated by radiotherapy for a skin hemangioma in childhood at Gustave Roussy between 1941 and 1973 and who have received less than 1 Gy of radiation doses in the brain * Inhabitants of Île-de-France * French medical insurance * Good knowledge and understanding of the French language Non-inclusion Criteria * Cerebral hemangioma * Syndrome genetic predisposition * Pregnant woman * Private person of liberty or under guardianship * Radiation dose to the brain greater than 1 Gy during radiotherapy treatment of skin hemangioma * Chemotherapy during skin hemangioma treatment * Inability to undergo counseling for geographical reasons Exclusion Criteria: * Pregnancy * Inability to perform neurocognitive tests battery for medical reasons

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Conditions

The condition(s) this trial relates to.

skin hemangioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Patients treated by radiotherapy with < one gy to the brain

Contacts and locations

Locations

  • Gustave Roussy

    Villejuif, France