Home-Based program aims to help long COVID patients breathe easier and move more
NCT ID NCT07661862
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a comprehensive, remotely delivered care program for people aged 40 and older with Long COVID who have ongoing heart or lung symptoms like fatigue, shortness of breath, or chest pain. The program includes medication review, mental health support, telehealth coaching, and a personalized 24-week exercise plan using a wearable sensor. Researchers measure whether participants can walk farther after 6 months, along with changes in quality of life, mental health, and heart function over two years.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- remote care program (medication review, mental health support, telehealth coaching, and personalized exercise program)
- What this could lead to
- If successful, this could provide a scalable, home-based care model to improve fitness and quality of life for people with Long COVID-related heart and lung issues.
- What could go wrong
- This is a single-arm study without a control group, so improvements may be due to natural recovery or other factors. The remote delivery may not suit everyone, and results may not apply to all Long COVID patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 577 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Apr 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged forty years or older * Impaired estimated functional capacity using DASI as proxy (defined by age-normative metabolic equivalent of tasks \[METs\]) * History of COVID-19 (stratified by hospital admission) * Currently symptomatic with fatigue, dyspnoea or chest pain symptoms * Medicare eligibility * Ability and willingness to provide written informed consent to participate in the study. The patient will need to be able to communicate fluently with the investigator. The investigator will need to be satisfied that the patient understands the study by having them explain the study plan back to the investigator. Exclusion Criteria: * Unable to provide written informed consent to participate in this study * Participating in another research trial where randomized treatment would be unacceptable * Mobility impairment that would impact participants' ability to perform exercise * History of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) * Known valvular stenosis or regurgitation of \>moderate severity, history of previous heart failure (baseline New York Heart Association \[NYHA\] \>2) * Oncologic (or other) life expectancy \<12 months or any other medical condition (including pregnancy) that results in the belief (deemed by the Chief Investigators) that it is not appropriate for the patient to participate in this trial
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Baker Heart and Diabetes Institute
NOT_YET_RECRUITINGMelbourne, Victoria, 3004, Australia
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Menzies Insititute for Medical Research
RECRUITINGHobart, Tasmania, 7009, Australia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can slow breathing retrain the nervous system to fight long COVID?
- Can a brain zapping headset restore focus after long COVID?
- Mindfulness may offer relief for long COVID sufferers
- Can wearables decode the mystery of fatigue?
- Beetroot juice: a natural boost against long COVID fatigue?
- A One-Two punch for long COVID? supplement and therapy put to the test