Can Low-Dose combo tame tough blood pressure in kidney disease?
NCT ID NCT07645300
First seen Jun 12, 2026 · Last updated Jun 16, 2026 · Updated 2 times
Summary
This study looks at whether low doses of two older blood pressure drugs, spironolactone and chlorthalidone, can safely lower blood pressure in people with moderate to advanced chronic kidney disease (CKD). About 160 U.S. Veterans with CKD and high blood pressure will take the drugs alone or together for up to 12 weeks. The goal is to find effective treatment options that manage blood pressure without causing dangerous side effects like high potassium levels.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Richard L. Roudebush VA Medical Center, Indianapolis, IN
Indianapolis, Indiana, 46202-2884, United States
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