Which nerve block works best for breast surgery pain?
NCT ID NCT06230575
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested four different nerve blocks (erector spinae, retrolaminar, serratus anterior, and pectoral nerve block) to see which one provides the longest pain relief after breast cancer surgery. 188 women aged 18 to 65 took part. The main goal was to measure how long it took before they needed rescue pain medication. The results help doctors choose the best block for managing post-surgery pain.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nerve block (erector spinae, retrolaminar, serratus anterior, or pectoral nerve block)
- What this could lead to
- If one block works best, it could become a standard way to manage pain after breast cancer surgery, reducing the need for strong painkillers.
- What could go wrong
- This is a completed, moderate-sized study, but it only looked at time to first painkiller dose, not long-term outcomes or side effects. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
188 people
The number who actually took part.
- Started
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Feb 2024
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * female cancer breast patient * age from 18- 65 Exclusion Criteria: * coagulation defect * Patient refusal * abnormal kidney and or liver function tests
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Walaa Y Elsabeeny
Cairo, 11796, Egypt
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