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Estrogen cream may help boys with birth defect heal better after surgery

NCT ID NCT01370798

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 30 times

Summary

This study tested whether applying estrogen cream to the penis for two months before surgery could reduce healing problems in 244 boys with severe hypospadias, a birth defect where the urethra doesn't form properly. The goal was to see if it lowers the risk of post-surgery complications like fistulas or wound separation. Results are not yet available.

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Contacts and locations

Locations

  • Hôpital Mère-Enfant

    Nantes, 44093, France

  • Hôpital NECKER

    Paris, 75015, France

  • Hôpital Robert Debré

    Paris, 72015, France

  • Service de Chirurgie Pédiatrique Uro-génitale, Hopital femme Mere Enfant

    Bron, 69677, France

Conditions

Explore the condition pages connected to this study.