Liver surgery showdown: which method spares the heart?
NCT ID NCT06895798
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 1,286 older adults or those with heart risks undergoing major liver surgery. It compared two methods of controlling blood flow to the liver to see which one causes less heart injury after surgery. The goal is to find safer surgical approaches and identify risk factors to prevent heart complications.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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1,286 people
The number who actually took part.
- Started
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Mar 2025
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
As of February 2024, patients ≥ 65 years old, or ≥ 45 years old with cardiovascular risk factors (especially known cardiovascular disease), who have undergone or are scheduled to undergo elective major hepatopancreatobiliary surgery under general anesthesia are being recruited/enrolled.
- Ages
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45 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 65 years, or ≥ 45 years with cardiovascular risk factors (especially known cardiovascular disease). * Undergoing elective major hepatopancreatobiliary surgery under general anesthesia. * ASA physical status II-III. * Provide written informed consent to participate in the study (applicable to the prospective cohort). Exclusion Criteria: * Emergency surgery * Preoperative diagnosis of myocardial infarction or unstable angina * Severe hepatic insufficiency (Child-Pugh class C) * Concomitant severe organ dysfunction (e.g., renal failure, respiratory failure) * Concomitant active infectious disease
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine,Tsinghua University
Beijing, Beijing Municipality, 102218, China
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Peking University International Hospital
Beijing, China
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Other studies related to the condition(s) this trial covers.
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