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Liver cancer drug combo vs. local therapy: trial ends early

NCT ID NCT05537402

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 34 times

Summary

This study aimed to compare two standard treatments for people with large intermediate-stage liver cancer that cannot be surgically removed. One group would receive a combination of two immunotherapy drugs (atezolizumab and bevacizumab), while the other would receive local treatments like chemoembolization or radioembolization. The trial was terminated after enrolling only one participant, so no meaningful results were obtained.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas

    Dallas, Texas, 75390, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

atezolizumab and bevacizumab (immunotherapy drugs)

What this could lead to

If successful, this could show that a drug combination works better than local treatments for certain liver cancer patients.

What could go wrong

The trial was terminated after enrolling only 1 person, so results are not available. It is too early to draw any conclusions.

Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.