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Blood test tracks lung cancer resistance in Real-World study

NCT ID NCT07475637

First seen Mar 24, 2026 · Last updated Jun 23, 2026 · Updated 21 times

Summary

This study looked at whether a simple blood test (liquid biopsy) can detect a specific resistance mutation called T790M in patients with advanced non-small cell lung cancer whose tumors stopped responding to initial targeted therapy. Researchers followed 70 patients in Tunisia, collecting blood samples and medical records to see how often the mutation appeared and if repeat testing improved detection. The goal was to understand how useful liquid biopsy is for monitoring resistance in everyday clinical practice.

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Contacts and locations

Locations

  • Pathology Department, Charles Nicolle Hospital of Tunis

    Tunis, 1007, Tunisia

Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.