Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Can a mushroom boost your brain? Lion's mane put to the test

NCT ID NCT07759687

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study investigates whether different doses of Lion's mane mushroom extract can improve attention and mood in healthy adults aged 18 to 45. Participants will receive the extract and a placebo in a crossover design, allowing each person to serve as their own control. The trial measures speed and accuracy of attention through cognitive tasks, aiming to identify the optimal acute dose for potential cognitive benefits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Lion's Mane fruiting bodies extract (20:1 ratio)
What this could lead to
If effective, Lion's mane could offer a natural, non-prescription option to sharpen attention and lift mood in healthy people.
What could go wrong
This is a small, early-stage study with only 24 participants, so results may not apply broadly. The extract's effects on attention and mood are not yet proven, and optimal dosing remains unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 24 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants must self-assess themselves as being in good health * Participants must be aged 18 to 45 at the time of giving consent * Understand and are willing to participate in all scheduled visits and to adhere to the trial procedures outlined in the subject information sheet * Are fluent in English (equivalent to IELTS Level 6) Exclusion Criteria: * Have any pre-existing medical condition/illness which will impact taking part in the study. There may be other, unforeseen, exceptions and these will be considered on a case-by-case basis, i.e., participants may be allowed to progress to screening if they have a condition/illness which would not interact with the active treatments or impede performance so it's worth discussing any medical conditions with the researcher prior to booking lab appointments. NOTE: the explicit exceptions to this is controlled hayfever, asthma, hypo/hyperthyroidism, high blood pressure, high cholesterol, reflux. * Are currently taking prescription medications NOTE: the explicit exceptions to this are contraceptive treatments, and those taken 'as needed' in the treatment of asthma and hay fever. There may be other instances of medication use which, where no interaction with the active treatments is likely, and which would not be expected to have any impact on brain function, participants may be able to progress to screening. * Have a history of experiencing difficulty swallowing tablets including in capsule form * Have high blood pressure (systolic over 139 mm Hg or diastolic over 89 mm Hg) * Have a Body Mass Index (BMI) outside of the range 18.5-35 kg/m2 (unless waist to hip ratio is less than or equal to 0.85 (female) or 0.90 (male)) * Engage in the extreme dietary habit of intermittent fasting, as judged by the Investigator * Are pregnant, seeking to become pregnant or lactating * Have been diagnosed with a neurological condition, or assessed as having a learning/behavioural or neurodevelopmental difference such as dyslexia, autism, or ADHD * Have a visual impairment that cannot be corrected with glasses or contact lenses (including colour-blindness) * Use illegal/recreational drugs * Have relevant food allergies/intolerances/ sensitivities * Consume over 500mg of caffeine per day * Have taken dietary supplements e.g., Vitamins, omega 3 fish oils etc. in the last 4 weeks (Note: participation is possible following a 4-week supplement washout prior to participating and for the duration of the study on the proviso that the supplements they are taken are out of choice and not medically prescribed or advised). NOTE - Vitamin D and iron supplements are allowed for this trial if they have been advised by GP to increase levels to a normal range and have been taken for at least 4 weeks consistently and will be taken consistently throughout the trial. * Are currently participating in any other chronic clinical or nutrition intervention studies, or have done so in the past 4 weeks * Have taken antibiotics within the past 4 weeks * Has been diagnosed with/ undergoing treatment for alcohol or drug abuse in the last 12 months * Have been diagnosed with/ undergoing treatment for a psychiatric disorder in the last 12 months (including medically diagnosed anxiety, depression or stress-related disorders). * Have any health condition that would prevent fulfilment of the study requirements (this includes non-diagnosed conditions for which no medications may be taken) * Suffers from frequent migraines that require medication (more than or equal to 1 per month) * Not be a native speaker of English or at least fluent in English * Smoke tobacco or vape nicotine or use nicotine replacement products * Have worked night shift the night prior to attending the laboratory * Are unable to demonstrate adequate minimal performance on lab, computer-based cognitive tasks * Have any known active infections * Do not have a bank account (required for payment)

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Attention are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Brain, Performance and Nutrition Research Centre

    Newcastle upon Tyne, Tyne and Wear, NE1 8ST, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.