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New light on colon polyps: can special imaging boost detection?

NCT ID NCT07127471

Disease control Sponsor: Evergreen General Hospital, Taiwan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 10, 2026 · Updated 3 times

Summary

This study compares two methods for finding precancerous colon polyps during colonoscopy. Both methods use water instead of air to inflate the colon and an AI system to spot polyps. One group also uses a special light filter called linked-color imaging. The goal is to see if the extra imaging helps find more of the tricky, flat polyps that can turn into cancer. About 1090 adults aged 40-80 will take part.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Linked-color imaging (LCI) and computer-aided detection (CADe) system
What this could lead to
If successful, this could improve detection of hard-to-see precancerous polyps during colonoscopy, potentially reducing colon cancer risk.
What could go wrong
This is a device comparison study, not a treatment trial. The improvement may be small or not clinically meaningful, and results may not apply to all colonoscopy settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 1,090 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male and female patients aged 40-80 years scheduled for average-risk screening colonoscopy, post-polypectomy surveillance, diagnosis for gastrointestinal symptoms (including unexplained iron deficiency anemia and clinically significant diarrhea of unexplained origin), or referred for colonoscopy owing to a positive fecal immunochemical test (FIT) or guaiac fecal occult blood test (gFOBT) result. Exclusion Criteria: * familial adenomatous polyposis and hereditary non-polyposis CRC syndrome * personal history of serrated polyposis syndrome * personal history of CRC * history of inflammatory bowel disease * previous colonic resection * overt gastrointestinal bleeding * emergency colonoscopy or inpatients * planned EMR or ESD of large polyps * colon stricture or obstruction * contraindications to colonoscopy (eg, acute diverticulitis or toxic megacolon) * antithrombotic therapy precluding complete polyp resection * American Society of Anesthesiology classification of physical status \>3 * pregnant women or women planning pregnancy * refusal to provide a written informed consent

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Conditions

The condition(s) this trial relates to.

colon adenoma colon sessile serrated adenoma/polyp colorectal sessile serrated adenoma/polyp polyp of colon polyp of large intestine

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colon adenomas Serrated lesion Sessile colonic polyp Sessile serrated lesion

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites in 4 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Evergreen General Hospital

    RECRUITING

    Taoyuan, 320, Taiwan

  • King Chulalongkorn Memorial Hospital

    NOT_YET_RECRUITING

    Bangkok, 10330, Thailand

  • Ospedale Valduce

    NOT_YET_RECRUITING

    Como, 22100, Italy

  • University of Montreal Medical Center (CHUM)

    NOT_YET_RECRUITING

    Montreal, Quebec, H2X 0A9, Canada

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