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Can an old antibiotic beat syphilis? new study tests linezolid

NCT ID NCT05548426

First seen Mar 16, 2026 · Last updated May 23, 2026 · Updated 10 times

Summary

This pilot study tests whether the antibiotic linezolid can effectively treat early syphilis (primary, secondary, or early latent). About 24 adults with a positive blood test will receive linezolid, and researchers will check if their blood test improves by at least 4-fold within 6 months. People with well-controlled HIV can also join. The goal is to find a new treatment option for syphilis.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Howard Brown Health

    Chicago, Illinois, 60613, United States

  • Open Arms HealthCare Center

    Jackson, Mississippi, 39216, United States

  • Open Door Health

    Providence, Rhode Island, 02907, United States

  • University of Mississippi Medical Center

    Jackson, Mississippi, 39216, United States

  • Wake Forest Baptist Health

    Greensboro, North Carolina, 27405, United States

Conditions

Explore the condition pages connected to this study.