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Light therapy shines as potential Drug-Free knee pain relief

NCT ID NCT07057063

Symptom relief Sponsor: The Hong Kong Polytechnic University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a special light (810 nm) can reduce knee pain and swelling in people with chronic knee pain and synovitis. About 80 adults aged 40-80 will receive either real light therapy or a sham treatment twice a week for five weeks. Researchers will measure pain, ultrasound images of the knee, and function to see if the light helps.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
810 nm light therapy
What this could lead to
If it works, this could offer a safe, non-invasive option to ease knee pain and inflammation without drugs or surgery.
What could go wrong
This is an early-stage trial with only 80 participants, so results may not apply to everyone. The sham group may also show improvement, making it hard to prove the light therapy's true effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants aged between 40 and 80 years * Able to provide written informed consent * Have experienced knee pain that persists or recurs for more than 3 months * A knee pain score of at least 30 mm on the 100-mm Visual Analogue Scale (VAS) during the past week * Ultrasound-measured knee synovitis ≥1 * Presence of knee OA according to criteria established by the American College of Rheumatology Exclusion Criteria: * Anticipated need for knee surgery within the next one year * Previous or planned knee replacement within the next one year * Knee surgery or other physical therapy in the previous 3 months * Use of intra-articular, intra-muscular, or oral corticosteroids in previous 4 weeks * Malignant tumors or other life-threatening diseases * Severe mental disorders, including but not limited to schizophrenia, bipolar disorder, or major depressive disorder, that may interfere with the participant's ability to comply with the study protocol or provide informed consent

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee synovitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee pain chronic Light therapy Synovitis of knee

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites in 2 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Buji Community Service Center, Longgang District

    RECRUITING

    Shenzhen, China

  • The Hong Kong Polytechnic University

    NOT_YET_RECRUITING

    Hong Kong, Hong Kong

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