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Personalized lifestyle coaching shows promise for AMD patients

NCT ID NCT05667441

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether personalized risk profiling (including genetic testing) and coaching can motivate people with age-related macular degeneration (AMD) to change their lifestyle. 150 participants received standard lifestyle advice plus supplements, and some also got personalized risk profiles and coaching. The goal was to see if these extra strategies improved lifestyle scores measured by questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
lifestyle recommendations, dietary supplements, risk profiling, coaching
What this could lead to
If successful, this could show that personalized advice and coaching help people with AMD stick to healthier habits, potentially slowing vision loss.
What could go wrong
This is a completed study that only measured lifestyle changes, not whether those changes actually prevent vision loss. Results may not apply to all AMD patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

150 people

The number who actually took part.

Started

Aug 2021

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

55 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Early/Intermediate AMD or unilateral late AMD with minimal vision 0.8 Exclusion Criteria: * Participation in other intervention studies for AMD * Living in retirement homes (difficulty in implementation of diet) * Diagnosis of dementia (because of unreliable dietary recall) * Persons with macular pathology other than AMD hindering appropriate grading of the macula * Persons who are illiterate and have no independent trusted person with them to explain the informed consent form. * Persons diagnosed with liver and kidney insufficiency.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Erasmus Medical Center

    Rotterdam, Netherlands

More trials for these conditions

Other studies related to the condition(s) this trial covers.