Personalized lifestyle coaching shows promise for AMD patients
NCT ID NCT05667441
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether personalized risk profiling (including genetic testing) and coaching can motivate people with age-related macular degeneration (AMD) to change their lifestyle. 150 participants received standard lifestyle advice plus supplements, and some also got personalized risk profiles and coaching. The goal was to see if these extra strategies improved lifestyle scores measured by questionnaires.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- lifestyle recommendations, dietary supplements, risk profiling, coaching
- What this could lead to
- If successful, this could show that personalized advice and coaching help people with AMD stick to healthier habits, potentially slowing vision loss.
- What could go wrong
- This is a completed study that only measured lifestyle changes, not whether those changes actually prevent vision loss. Results may not apply to all AMD patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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150 people
The number who actually took part.
- Started
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Aug 2021
- Finished
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Jul 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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55 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Early/Intermediate AMD or unilateral late AMD with minimal vision 0.8 Exclusion Criteria: * Participation in other intervention studies for AMD * Living in retirement homes (difficulty in implementation of diet) * Diagnosis of dementia (because of unreliable dietary recall) * Persons with macular pathology other than AMD hindering appropriate grading of the macula * Persons who are illiterate and have no independent trusted person with them to explain the informed consent form. * Persons diagnosed with liver and kidney insufficiency.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Erasmus Medical Center
Rotterdam, Netherlands
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Other studies related to the condition(s) this trial covers.
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