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Former athletes at risk? study links old injuries and sedentary habits to poor health

NCT ID NCT05344001

Knowledge-focused Sponsor: Marquette University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how past sports injuries and a sedentary lifestyle may lead to chronic disease, pain, and disability in former athletes. Researchers will compare strength, function, physical activity, and heart health among current and former college athletes and non-athletes aged 18-25 or 40-64. The goal is to understand long-term health risks and inform future prevention strategies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could identify key factors that lead to poor health in former athletes, pointing toward ways to prevent chronic disease and disability later in life.
What could go wrong
This is an observational study, not a treatment trial. It will not directly improve health, and results may not apply to all former athletes or non-athletes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 450 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2022

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Current and former collegiate varsity athletes with and without a prior history of traumatic knee injury and matched non-athlete controls.

Ages

18 to 64 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Please see cohorts for specific inclusion/exclusion criteria Inclusion Criteria: * Age 18-25 years OR age 40-64 years * Current or former collegiate varsity athlete OR non-athlete control Exclusion Criteria: * Neurologic (e.g., stroke, Parkinson's) and/or degenerative disease that impairs function * Pregnancy * Lower extremity joint replacement (e.g., hip or knee replacement)

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Conditions

The condition(s) this trial relates to.

Athletic Injuries disease injury Knee Injuries Motor Activity Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging Athletic injuries Knee injuries and disorders Physical inactivity

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Marquette University

    RECRUITING

    Milwaukee, Wisconsin, 53233, United States

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