Lidocaine may replace opioids for Post-Surgery pain
NCT ID NCT07312877
First seen Jun 24, 2026 · Last updated Aug 13, 2026 · Updated 3 times
Summary
This study tested whether lidocaine, a common numbing drug, works as well as remifentanil (an opioid) for pain after laparoscopic gallbladder removal. 138 adults took part. The goal is to find effective pain relief with fewer opioid side effects.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- lidocaine and remifentanil
- What this could lead to
- If lidocaine works as well as remifentanil, it could offer a safer, opioid-sparing option for pain control after gallbladder surgery.
- What could go wrong
- This is a small, completed observational study, not a large randomized trial. Results may not apply to other surgeries or patient groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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138 people
The number who actually took part.
- Started
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Apr 2025
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients (ASA I-II) undergoing elective laparoscopic cholecystectomy under general anesthesia at Prof. Dr. Cemil Taşçıoğlu City Hospital.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients over 18 years of age * ASA physical status I-II * Scheduled for elective laparoscopic cholecystectomy under general anesthesia * Provided written and verbal informed consent Exclusion Criteria: * Allergy or contraindication to lidocaine, remifentanil, or study drugs * Severe cardiovascular, hepatic, or renal disease * Pregnancy or lactation * Conversion from laparoscopic to open cholecystectomy * Refusal to participate
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Prof. Dr. Cemil Tascıoğlu City Hospital
Istanbul, Istanbul, 34384, Turkey (Türkiye)