Could a simple lidocaine drip make thyroid surgery safer and smoother?
NCT ID NCT06785987
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving a continuous lidocaine drip during thyroid surgery can improve anesthesia depth and reduce side effects like nausea and low blood pressure. About 100 adults having open thyroid surgery with nerve monitoring will take part. The goal is to see if lidocaine helps patients stay still and recover more comfortably.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2024
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 20-75 years old * Receiving open thyroid surgery * Using intraoperative neurophysiological monitoring Exclusion Criteria: * Allergic to opioids or lidocaine. * Unsuitable for prolonged lidocaine infusion due to impaired cardiac function or severe arrhythmias. * Impaired renal function (eGFR \< 30). * Liver dysfunction (Child-Pugh score B/C).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Kaohsiung veterans general hospital
Kaohsiung, Taiwan, 813, Taiwan
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Other studies related to the condition(s) this trial covers.
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