Could a common numbing drug slash opioid needs in sickle cell crises?
NCT ID NCT07274254
First seen Jan 07, 2026 · Last updated May 24, 2026 · Updated 23 times
Summary
This study tests whether adding lidocaine to standard pain treatment can lower the amount of strong opioids needed by adults with sickle cell disease during a severe pain crisis in the ICU. About 104 participants will be randomly assigned to receive either lidocaine or a placebo alongside usual care. The goal is to see if lidocaine helps control pain while reducing opioid use and side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHRU Tours - Hôpital Bretonneau
Tours, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Bordeaux
Bordeaux, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Guadeloupe
Les Abymes, Guadeloupe
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU La Timone
Marseille, France
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CHU Lille
Lille, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Orléans
Orléans, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Poitiers
Poitiers, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU Rouen
Rouen, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU de Nantes
Nantes, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Tenon APHP
Paris, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Oncopole Toulouse
Toulouse, France
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Conditions
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