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Could a common numbing drug replace morphine after surgery?

NCT ID NCT07419815

Symptom relief Sponsor: Shaukat Khanum Memorial Cancer Hospital & Research Centre Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Aug 25, 2026 · Updated 3 times

Summary

This study tests whether giving lidocaine through a vein during surgery can lower pain and the need for morphine afterward. Sixty-two adults having staging laparoscopy will receive either lidocaine or a saltwater placebo. The goal is to see if lidocaine can reduce opioid side effects like nausea and breathing trouble.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
lidocaine
What this could lead to
If it works, this could offer a way to control pain after surgery using less morphine, reducing nausea, vomiting, and breathing problems.
What could go wrong
This is a small, early-stage trial with only 62 people. Lidocaine may not work better than placebo, and there is a risk of allergic reactions or side effects from the infusion.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

62 people

The number who actually took part.

Started

Dec 2025

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age between 18 to 60 years. 2. American Society of Anesthesiologists grade 1 and 2 patients. 3. Both Genders 4. Elective staging Laparoscopy Exclusion Criteria: 1. Patients allergic to lidocaine. 2. Patients refusal. 3. Patients having a history of chronic pain. 4. Patients already using opioids for pain control 5. Use of suxamethonium. 6. Procedures taking longer than 60 minutes

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Conditions

The condition(s) this trial relates to.

Acute Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Side effects of opoid consumption

Contacts and locations

Locations

  • Shaukat Khanam Memorial Cancer Hospital & Research Centre

    Lahore, Punjab Province, 54470, Pakistan