Could a common numbing drug replace morphine after surgery?

NCT ID NCT07419815

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving lidocaine through a vein during surgery can lower pain and the need for morphine afterward. Sixty-two adults having staging laparoscopy will receive either lidocaine or a saltwater placebo. The goal is to see if lidocaine can reduce opioid side effects like nausea and breathing trouble.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lidocaine

What this could lead to

If it works, this could offer a way to control pain after surgery using less morphine, reducing nausea, vomiting, and breathing problems.

What could go wrong

This is a small, early-stage trial with only 62 people. Lidocaine may not work better than placebo, and there is a risk of allergic reactions or side effects from the infusion.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Acute Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shaukat Khanam Memorial Cancer Hospital & Research Centre

    Lahore, Punjab Province, 54470, Pakistan