Can a supplement duo boost fertility in women with PCOS?
NCT ID NCT07266259
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether taking levocarnitine together with myoinositol works better than myoinositol alone for improving insulin resistance and hormone levels in women with PCOS who have trouble getting pregnant. 72 women aged 18-40 with insulin-resistant PCOS will take either the combination or myoinositol alone for 3 months. Researchers will measure changes in insulin resistance and hormone levels to see if the combo offers extra benefits.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Levocarnitine and myoinositol (dietary supplements)
- What this could lead to
- If it works, this could point toward a better supplement combination for managing insulin resistance and hormone levels in women with PCOS who have trouble getting pregnant.
- What could go wrong
- This is a small, early-stage trial with only 72 participants and no blinding, so results may not be reliable or apply to everyone. The supplements may not work better than myoinositol alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 72 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age:18-40 years old. * Diagnosed cases of PCOS patients(both old \& new cases) according to International evidence-based guideline criteria 2023 * Primary or secondary subfertility. * Insulin resistance (HOMA-IR \>2.6) Exclusion Criteria: * Hypothyroidism * Diabetes mellitus * Hormonal (Myo-inositol,D-chiro-inositol) or insulin sensitizing drugs like Metformin,Pioglitazone etc. treatment in the last three months * Known hypersensitivity to Myo-inositol and Levo-carnitine * Pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Bangladesh Medical University
NOT_YET_RECRUITINGDhaka, Shahbag, 1000, Bangladesh
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Bangladesh Medical University
RECRUITINGDhaka, Shahbag, 1000, Bangladesh
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- Sugar-Alcohol combo may restore periods in PCOS
- Could a diabetes drug boost pregnancy success in women with PCOS?