Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New hope for rare blood cancer: lenalidomide dose study shows promise

NCT ID NCT02302469

Disease control Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested the drug lenalidomide in 17 people with Waldenstrom macroglobulinemia, a rare blood cancer, that had returned or stopped responding to prior treatments. The main goal was to find the safest dose by monitoring side effects. Researchers also looked at how many patients responded to the drug.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

17 people

The number who actually took part.

Started

Mar 2009

Finished

Apr 2017

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: The most important criteria for patient eligibility include: 1. Age \>=18 years 2. Patients must have received prior therapy (any number of therapies) for WM and have relapsed or refractory WM 3. Eastern Cooperative Oncology Group performance score of 0 - 2 4. Hemoglobin \>= 10g/dL or hematocrit \>= 30% 5. Absolute neutrophil count (ANC) \>1000/mm3 and platelet count \>75,000/mm3 6. Adequate organ function defined as * serum glutamate pyruvate transaminase and serum glutamate oxaloacetate transaminase \< 2 x International Unit/l * Total bilirubin \>= 1.5 mg/dL * Clearance creatinin \> 50 ml/mn 7. Evaluable immunochemical abnormalities including abnormal electrophoresis and serum free light chain assay with an increase of either kappa or lambda light chain lev - Exclusion Criteria: Key Exclusion criteria 1. Any other uncontrolled medical condition or comorbidity that might interfere with subject's participation 2. Patients treated or requiring corticosteroids \>30mg/day 3. Pregnant or breast feeding females (Lactating females must agree not to breast feed while taking lenalidomide) 4. Use of any other experimental drug or therapy within 28 days of baseline 5. The development of erythema nodosum if characterized by a desquamating rash while taking thalidomide or similar drugs 6. Known positive for HIV or infectious hepatitis, type A, B or C -

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Waldenstrom macroglobulinemia are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Waldenstrom macroglobulinemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Waldenstrom macroglobulinemia

Contacts and locations

Locations

  • CH LENS

    Lens, 62307, France

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite, 69495, France

  • Centre Hospitalier de la côte basque

    Bayonne, 64109, France

  • Ch Clermond Ferrand

    Clermont-Ferrand, 63000, France

  • Ch Nantes

    Nantes, 44 093, France

  • Chru Lille

    Lille, 59037, France

  • Groupe hospitalier Pitié Salpétrière

    Paris, 75651, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.