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Old drug, new hope for rare skin cancer?

NCT ID NCT01556035

First seen May 14, 2026 · Last updated Jun 23, 2026 · Updated 6 times

Summary

This study tested the drug lenalidomide (Revlimid) in 19 people with a rare type of skin lymphoma called leg-type large B-cell lymphoma that had come back or not responded to initial chemotherapy. Participants took lenalidomide pills daily for 21 days, then rested for 7 days, repeating this cycle for up to a year. The main goal was to see how many patients had their tumors shrink or disappear after 6 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AP-HM Hôpital Nord

    Marseille, 13915, France

  • AP-HP Groupe hospitalier Bichat - Claude Bernard

    Paris, 75877, France

  • AP-HP Groupe hospitalier Cochin

    Paris, 75679, France

  • AP-HP Hôpital Ambroise Paré

    Boulogne-Billancourt, 92104, France

  • AP-HP Hôpital Avicenne

    Bobigny, 93009, France

  • AP-HP Hôpital Henri Mondor

    Créteil, 94010, France

  • AP-HP Hôpital Tenon

    Paris, 75970, France

  • AP-HP- Hôpital Saint Louis

    Paris, 75475, France

  • CHRU de Montpellier Hôpital Saint-Eloi

    Montpellier, 34295, France

  • CHU Amiens, Hôpital Sud

    Amiens, 80054, France

  • CHU Besançon, Hôpital Saint-Jacques

    Besançon, 25030, France

  • CHU Lyon Sud

    Pierre-Bénite, 69450, France

  • CHU de Bordeaux Hôpital du Haut Lévèque

    Pessac, 33604, France

  • CHU de Clermont-Ferrand, Estaing

    Clermont-Ferrand, 63003, France

  • CHU de Dijon, Le Bocage

    Dijon, 21079, France

  • CHU de Grenoble

    Grenoble, 38043, France

  • CHU de Lille Hôpital Claude Huriez

    Lille, 59037, France

  • CHU de Nantes, Hôtel Dieu

    Nantes, 44093, France

  • CHU de Nice Groupe hospitalier l'Archet

    Nice, 06202, France

  • CHU de Reims, Hôpital Robert Debré

    Reims, 51092, France

  • CHU de Rouen, Hôpital Charles Nicolle

    Rouen, 76031, France

  • CHU de Toulouse Hôpital Larrey

    Toulouse, 31059, France

  • CHU de Tours- Hôpital Trousseau

    Tours, 37044, France

  • Centre Léon Bérard

    Lyon, 69373, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lenalidomide (Revlimid)

What this could lead to

If it works, this could offer a new treatment option for people with this rare skin lymphoma that has come back after initial therapy.

What could go wrong

This is a small, early-phase trial with only 19 participants, so results may not apply broadly. Lenalidomide can cause side effects like low blood counts and fatigue.

Conditions

The condition(s) this trial relates to.

primary cutaneous diffuse large B-cell lymphoma, Leg type

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.