Old drug, new hope for rare skin cancer?

NCT ID NCT01556035

Completed Disease control Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested the drug lenalidomide (Revlimid) in 19 people with a rare type of skin lymphoma called leg-type large B-cell lymphoma that had come back or not responded to initial chemotherapy. Participants took lenalidomide pills daily for 21 days, then rested for 7 days, repeating this cycle for up to a year. The main goal was to see how many patients had their tumors shrink or disappear after 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lenalidomide (Revlimid)
What this could lead to: If it works, this could offer a new treatment option for people with this rare skin lymphoma that has come back after initial therapy.
What could go wrong: This is a small, early-phase trial with only 19 participants, so results may not apply broadly. Lenalidomide can cause side effects like low blood counts and fatigue.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

primary cutaneous diffuse large B-cell lymphoma, Leg type

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

REFRACTORY PRIMARY-CUTANEOUS LARGE B-CELL LYMPHOMA (LEG-TYPE)

Contacts and locations

Locations

AP-HM Hôpital Nord

Marseille, 13915, France
AP-HP Groupe hospitalier Bichat - Claude Bernard

Paris, 75877, France
AP-HP Groupe hospitalier Cochin

Paris, 75679, France
AP-HP Hôpital Ambroise Paré

Boulogne-Billancourt, 92104, France
AP-HP Hôpital Avicenne

Bobigny, 93009, France
AP-HP Hôpital Henri Mondor

Créteil, 94010, France
AP-HP Hôpital Tenon

Paris, 75970, France
AP-HP- Hôpital Saint Louis

Paris, 75475, France
CHRU de Montpellier Hôpital Saint-Eloi

Montpellier, 34295, France
CHU Amiens, Hôpital Sud

Amiens, 80054, France
CHU Besançon, Hôpital Saint-Jacques

Besançon, 25030, France
CHU Lyon Sud

Pierre-Bénite, 69450, France
CHU de Bordeaux Hôpital du Haut Lévèque

Pessac, 33604, France
CHU de Clermont-Ferrand, Estaing

Clermont-Ferrand, 63003, France
CHU de Dijon, Le Bocage

Dijon, 21079, France
CHU de Grenoble

Grenoble, 38043, France
CHU de Lille Hôpital Claude Huriez

Lille, 59037, France
CHU de Nantes, Hôtel Dieu

Nantes, 44093, France
CHU de Nice Groupe hospitalier l'Archet

Nice, 06202, France
CHU de Reims, Hôpital Robert Debré

Reims, 51092, France
CHU de Rouen, Hôpital Charles Nicolle

Rouen, 76031, France
CHU de Toulouse Hôpital Larrey

Toulouse, 31059, France
CHU de Tours- Hôpital Trousseau

Tours, 37044, France
Centre Léon Bérard

Lyon, 69373, France