Could a hidden nerve condition be more common in lung cancer than we think?
NCT ID NCT07075627
First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time
Summary
This study is looking at how often people with small cell lung cancer also have symptoms of Lambert-Eaton myasthenic syndrome (LEMS), a condition that affects the nerves and can cause muscle weakness. Researchers will review medical records and check for LEMS symptoms in adults diagnosed with small cell lung cancer. The goal is to better understand how common this condition is in this group of patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If this study succeeds, it could lead to better awareness and earlier detection of LEMS in people with small cell lung cancer, potentially improving their quality of life.
- What could go wrong
- This is an observational study, so it won't test any treatment. It may not capture all cases of LEMS, and the findings might not apply to everyone with small cell lung cancer.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Expected to start
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Sep 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
United States
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Adult men or women meeting Age of Majority (AOM) at the time of consent 2. Provide voluntary consent to participate in this study, documented via a signed informed Consent Form (ICF) 3. Any diagnosis of SCLC 4. Willing to provide clinical and medical information related to his/her cancer diagnoses to the study team as required 5. Willing to comply with the requirements of the study Exclusion Criteria: 1. Has been diagnosed with non-tumor Lamber-Eaton Myasthenic syndrome (LEMS) \> 1 year prior to the SCLC diagnosis. 2. Known existence of an uncontrolled intercurrent illness including, but not limited to, psychiatric illness or social situations that would impair compliance with study requirements
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Other studies related to the condition(s) this trial covers.
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