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Heart bypass study tests best way to close leg wounds

NCT ID NCT07355452

Knowledge-focused Sponsor: National Institute of Cardiovascular Diseases, Pakistan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two methods of closing the leg incision after taking a vein for heart bypass surgery: a single-layer stitch versus a multi-layer stitch. Researchers will track 200 patients for one week to see which method leads to fewer wound infections, hematomas, or other complications. The goal is to find the safest and most effective closure technique.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If one closure method proves better, it could reduce wound complications and hospital stays for heart bypass patients.
What could go wrong
This is a small, early-stage study (200 patients) comparing surgical techniques, not testing a new drug or cure. Results may not apply to all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2025

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Sample Selection Sampling Technique: Non-probability consecutive sampling Inclusion Criteria: * elective CABG * Both male and female patients * Patient of age between 18-70 years * Patients of consenting surgeons will be included in the study after elaboration of study protocol Exclusion Criteria: * Patients with previous leg surgery, * peripheral vascular disease, * obesity, BMI; \>30kg/m 2 .(weight in kilogram, height in meters) * varicose veins * those undergoing total arterial revascularization * emergency CABG

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Hematoma Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Asepsis score Hematoma Prolonged hospital stay Readmission rates Seroma following procedure Surgical site infection (SSI) Surgical wound infection

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • National Institute of cardiovascular diseases

    Karachi, Sindh, 75510, Pakistan

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Other studies related to the condition(s) this trial covers.