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Could a cheap arthritis drug replace steroids for transplant patients?

NCT ID NCT04932564

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 31 times

Summary

This study tested leflunomide, a drug used for rheumatoid arthritis, as a first treatment for musculoskeletal graft-versus-host disease (GVHD) in transplant patients. GVHD occurs when donor cells attack the patient's body, often affecting muscles and joints. The goal was to see if leflunomide could work as well as steroids but with fewer side effects. Only one person enrolled before the study was stopped early.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Tata Memorial Centre, Advanced Centre for Treatment, Research and Education in Cancer

    Navi Mumbai, Maharashtra, 410210, India

Conditions

Explore the condition pages connected to this study.