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Scientists hunt for genetic clues behind rare childhood disease

NCT ID NCT04100408

First seen Jan 11, 2026 · Last updated May 22, 2026 · Updated 21 times

Summary

This study looks at how inherited genes may make some children more likely to develop Langerhans cell histiocytosis (LCH), a rare disease where immune cells grow out of control. Researchers will analyze DNA from 647 children and their parents to find gene changes linked to LCH and understand why tumor mutations differ by race. The goal is to learn more about what causes LCH, not to test a new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.