Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New pacemaker technique may cut AF risk in heart patients

NCT ID NCT07250529

Disease control Sponsor: University Hospital of Patras Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two ways of placing a pacemaker lead in people who need frequent pacing. One method (left bundle branch pacing) aims to activate the heart more naturally than the standard method. The goal is to see if it reduces the time the heart spends in fast, irregular rhythms that can lead to atrial fibrillation. About 244 adults with normal heart pumping function will take part.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Left bundle branch pacing (a type of pacemaker lead placement)
What this could lead to
If it works, this could point toward a better pacing method that lowers the risk of developing atrial fibrillation in people who need a pacemaker.
What could go wrong
This is a relatively small, early-stage trial (244 participants) comparing two pacing techniques. The benefit may be modest, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 244 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Jun 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years * Scheduled implantation of a dual-chamber pacemaker for: Permanent complete heart block Permanent second-degree AV block (Mobitz II or Mobitz I) * Documented preserved LVEF (≥50%) * Sinus rhythm at baseline * Ability to provide written informed consent Exclusion Criteria: * History of paroxysmal, persistent, or permanent atrial fibrillation * Previous atrial fibrillation ablation (catheter-based or surgical) * LVEF \< 50% * Sinus node disease * Transient AV block requiring pacemaker implantation * Significant structural or valvular heart disease * Requirement for pacemaker system upgrade during the study period * Requirement for antiarrhythmic therapy for causes other than atrial fibrillation * Existing pacemaker or other cardiac device requiring modification for study participation * Enrollment in another clinical trial that could interfere with study endpoints or pacing parameters * Contraindication to LBBP or associated lead implantation procedure * Life expectancy \< 12 months * Any condition judged by the investigator to compromise participation or the integrity of study data

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Atrial fibrillation (AF) are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

atrial fibrillation atrioventricular block heart failure second-degree atrioventricular block third-degree atrioventricular block

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atrial fibrillation (AF) Atrioventricular block Pacemaker therapy Preserved ejection fraction

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University General Hospital of Patras

    RECRUITING

    Pátrai, Greece

More trials for these conditions

Other studies related to the condition(s) this trial covers.