Laughing gas lifts depression: brain scans reveal how
NCT ID NCT05528718
First seen Mar 30, 2026 · Last updated May 20, 2026 · Updated 9 times
Summary
This small pilot study tested whether laughing gas (nitrous oxide) can improve mood in people with major depression. Eleven participants received either laughing gas or a sedative (midazolam), and researchers used MRI brain scans to look for changes in brain activity. The goal was to see how the treatment might work in the brain, not to prove it is a cure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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St. Michael's Hospital
Toronto, Ontario, M5B 1M8, Canada
Conditions
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