Hospital staff TB screening under review: are routine tests necessary?
NCT ID NCT07608601
First seen Jun 24, 2026 · Last updated Sep 03, 2026 · Updated 3 times
Summary
This study looks back at records of over 1,000 new hospital workers in Nice, France, who were tested for latent (hidden) tuberculosis infection as part of their hiring process. The goal is to see how many test positive, what factors increase the risk, and whether the screening leads to useful follow-up like chest X-rays or preventive treatment. The results will help decide if routine testing for all new staff is a good use of resources.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help hospitals decide whether routine TB screening for new staff is worthwhile, potentially saving costs and focusing efforts on high-risk groups.
- What could go wrong
- This is a retrospective observational study, so it can only show patterns, not prove cause and effect. The results may not apply to other hospitals or regions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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1,185 people
The number who actually took part.
- Started
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Apr 2024
- Finished
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Apr 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of newly recruited hospital workers at the University Hospital of Nice who underwent pre-employment occupational health assessment and QuantiFERON-TB Gold Plus screening during the study period. The population includes medical, paramedical, medico-technical, administrative, technical, logistical, transport and support staff, with or without direct patient contact.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Newly recruited hospital workers at the University Hospital of Nice. * Workers who underwent pre-employment occupational health assessment during the study period. * Workers who had a QuantiFERON-TB Gold Plus test performed as part of pre-employment screening. Exclusion Criteria: * Incomplete or unusable occupational health records. * Indeterminate QuantiFERON-TB Gold Plus results will be included in the descriptive analysis but excluded from comparative analyses of test positivity.
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU de NICE
Nice, Alpes Maritimes, 06000, France
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Other studies related to the condition(s) this trial covers.
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