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Can a laser replace the drill to spare kids dental pain?

NCT ID NCT07759739

Symptom relief Sponsor: Ege University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial asks whether using a laser instead of a traditional drill to prepare cavities can reduce pain, anxiety, and discomfort in children aged 6 to 12 with molar-incisor hypomineralization (a condition causing weak enamel). Half of the 52 participants will have cavities prepared with an Er:YAG laser, and the other half with a standard rotary drill. Researchers will measure pain, anxiety, heart rate, need for local anesthesia, and how well the fillings hold up over six months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Er:YAG laser-assisted cavity preparation
What this could lead to
If laser preparation proves less painful and anxiety-provoking, it could become a preferred method for treating children with this condition, improving their dental experience.
What could go wrong
This is a small, early-stage trial, and results may not apply to all children. Laser equipment is costly, and not all dental practices may adopt it.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 52 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

6 to 12 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Children aged 6 to 12 years. * Diagnosis of molar-incisor hypomineralization according to the European Academy of Paediatric Dentistry diagnostic criteria. * Presence of mild or moderate molar-incisor hypomineralization. * Presence of an erupted mandibular first permanent molar (tooth 36 or 46) requiring restorative treatment. * Presence of a single-surface occlusal carious lesion classified as ICDAS code 4 or 5. * Vital target tooth without clinical or radiographic signs of pulpal or periapical pathology. * No previous restorative treatment of the target tooth. * Cooperative behavior corresponding to Frankl behavior rating scores 3 or 4 and Venham scores 0 to 2. * Written informed consent provided by a parent or legal guardian. * Child assent to participate in the study. Exclusion Criteria: * Presence of a systemic or neurodevelopmental condition that could affect pain perception, anxiety, communication, or cooperation. * Use of analgesic, anxiolytic, sedative, or other medication that could influence pain or anxiety assessment before treatment. * Presence of spontaneous dental pain, irreversible pulpitis, pulp necrosis, or periapical pathology in the target tooth. * Requirement for multisurface cavity preparation or extensive restorative treatment. * Previous restorative treatment of the target tooth. * Inability of the child or parent/legal guardian to understand or complete the study assessments. * Refusal of the child or parent/legal guardian to participate.

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Conditions

The condition(s) this trial relates to.

Molar Hypomineralization Toothache

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Molar-incisor hypomineralization (MIH)

Contacts and locations

Locations

  • Ege University, Faculty of Dentistry, Department of Pediatric Dentistry

    Izmir, İzmir, 35100, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.