Laser zaps annoying eye floaters in new trial
NCT ID NCT05800353
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tested whether a laser procedure (Nd:YAG vitreolysis) can safely reduce symptoms from bothersome eye floaters, specifically a type called Weiss ring. Seventy adults with floaters for at least one month were randomly assigned to get the laser treatment either right away or after a three-month delay. The study measured how much their symptoms improved and changes in vision-related quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Nd:YAG laser vitreolysis (laser procedure to break up eye floaters)
- What this could lead to
- If it works, this could offer a safe, non-surgical option to reduce bothersome eye floaters and improve vision-related quality of life.
- What could go wrong
- This is a small, single-center trial with 70 participants. The laser may not improve symptoms for everyone, and risks like eye inflammation or vision changes are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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70 people
The number who actually took part.
- Started
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Nov 2022
- Finished
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Dec 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Self-rating of visual disturbance by the floaters must be at least 4 on a 0-10 scale, with 0 being no symptoms to 10 being debilitating symptoms. 2. Symptomatic Weiss ring (PVD) must be at least 2mm away from the retina and 5 mm from the posterior lens capsule of the crystalline lens, as measured on B-scan. For pseudophakic patients, there is no minimum required distance from the intraocular lens. 3. Able to position for the YAG laser procedure. 4. Accept the risks of YAG laser including but not limited to retinal detachment, intraocular hemorrhage, retinal damage, cataract formation, optic nerve damage, inflammation, and irreversible loss of vision. 5. Willing and able to comply with clinic visits and study-related procedures 6. If the patient has two symptomatic eyes, only one eye can be randomized and included in the study. 7. Provide signed informed consent Exclusion Criteria: 1. History of retinal tear, retinal detachment, or uveitis in the study eye 2. History of diabetic retinopathy, macular edema, retinal vein occlusion, or aphakia in the study eye 3. History of glaucoma or high intraocular pressure defined as having a history of glaucoma surgery or currently taking two or more topical glaucoma medications in the study eye
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dongyang People's Hospital
Dongyang, Zhejiang, 322100, China